Browsing Obstetrics & Gynaecology (Theses and Dissertations) by Title
Now showing items 3-8 of 8
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Phytoestrogens as an alternative to HRT : an investigation into the molecular effects of phytoestrogens on haemostasis in cell and animal models
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Obstetrics and Gynaecology, 2011)There is a direct link between the increased risk of cardiovascular disease and the menopause and this is thought to be due to the progressive lack of endogenous oestrogen in post-menopausal women. Observational studies ... -
Predicting the response of gynaecological tumours to chemotherapy
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Obstetrics and Gynaecology, 2003)The aim of this study was to use an in vitro (3-(4,5-dimethylthiazol-2-yl)-5-(3- carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt) (MTS) assay in combination with an explant culture technique to determine ... -
Prediction of pre-eclampsia
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Obstetrics and Gynaecology, 2003)Pre-eclampsia occurs in 2-10% of pregnancies and is a leading cause of maternal and perinatal morbidity and mortality. The serious shortcoming associated with management is that the underlying aetiology is unknown. To date ... -
The influence of inherited thrombophilia, endothelial activation and fibrinolysis on placental morphology and vasculature and on maternal and fetal outcome, in a low risk primigravid population
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Obstetrics and Gynaecology, 2009)A number of inherited thrombophilias have been associated with adverse events occurring during pregnancy. A common feature of these abnormalities is their ability to alter endothelial function and to increase thrombin ... -
Ultrasound to enhance assessment of the fetal head position prior to instrumental delivery
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Obstetrics and Gynaecology, 2013)This thesis is aimed at investigating the role of ultrasound to enhance diagnosis of the fetal head position prior to instrumental delivery in order to make instrumental deliveries safer.There are four components to this ... -
Uteroplacental fibrinolysis in normal pregnancy, preeclampsia and intrauterine growth retardation
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Obstetrics and Gynaecology, 2000)Normal pregnancy is accompanied by extensive changes in the coagulation and fibrinolytic systems. Within the uteroplacental vasculature decidual spiral arteries undergo extensive morphological changes to allow for increased ...