Browsing Mechanical & Manufacturing Eng (Scholarly Publications) by Title
Now showing items 303-322 of 636
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The identification of articular cartilage and growth plate extracellular matrix-specific proteins supportive of either osteogenesis or stable chondrogenesis of stem cells
(2020)Tissue-specific extracellular matrix (ECM) proteins can play a key role in regulating the fate of stem cells and can potentially be utilized for therapeutic applications. Realising this potential requires further ... -
Identification of mechanosensitive genes during skeletal development: Alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways
(2014)Background Mechanical stimulation is necessary for regulating correct formation of the skeleton. Here we test the hypothesis that mechanical stimulation of the embryonic skeletal system impacts expression levels of genes ... -
Imaging arterial fibres using diffusion tensor imaging - feasibility study & preliminary results
(2010)MR diffusion tensor imaging (DTI) was used to analyze the fibrous structure of aortic tissue. A fresh porcine aorta was imaged at 7T using a spin echo sequence with the following parameters: matrix 128 ? 128 pixel; slice ... -
The Impact of Additive Manufacturing on the Acoustic Performance of Novel Porous Materials
(2022)Commonly used conventional acoustic porous materials suffer from a limited operational frequency range and great dependency of the sample thickness on their performance. For this reason, acoustic metamaterials have caught ... -
The impact of decellularization methods on extracellular matrix derived hydrogels.
(2019)Tissue-derived decellularized biomaterials are ideal for tissue engineering applications as they mimic the biochemical composition of the native tissue. These materials can be used as hydrogels for cell encapsulation and ... -
Implementation of a CDIO compliant syllabus in a large engineering programme
(2008)The role of the engineer in industry has evolved, with to day’s engineering businesses seeking engineers with abilities and attributes in two broad areas - te chnical understanding and enabling skills. Institutions ... -
Implementation of Project Based Learning in a Large Engineering Programme
(2010)The role of the engineer in industry has evolved, with today?s engineering businesses seeking engineers with abilities and attributes in two broad areas - technical understanding and enabling skills. Institutions within ... -
Improvement of tensile strength of cold sprayed Fe deposits via in-process powder preheating
(2022)Cold sprayed Fe deposits were manufactured with non-preheated and preheated powders, respectively. The microstructure of the deposits was characterized by electron backscattered diffraction. The tensile property of the ... -
Improving the intercellular uptake and osteogenic potency of calcium phosphate via nanocomplexation with the RALA peptide
(2020)Calcium phosphate-base materials (e.g., alpha tri-calcium phosphate (α–TCP)) have been shown to promote osteogenic differentiation of stem/progenitor cells, enhance osteoblast osteogenic activity and mediate in vivo bone ... -
In vitro co-culture and ex vivo organ culture assessment of primed and cryopreserved stromal cell microcapsules for intervertebral disc regeneration
(2019)Priming towards a discogenic phenotype and subsequent cryopreservation of microencapsulated bone marrow stromal cells (BMSCs) may offer an attractive therapeutic approach for disc repair. It potentially obviates ... -
In vivo dynamics of the internal fibrous structure in smooth adhesive pads of insects
(2012)Many insects with smooth adhesive pads can rapidly enlarge their contact area by centripetal pulls on the legs, allowing them to cope with sudden mechanical perturbations such as gusts of wind or raindrops. The short time ... -
Incorporation of collagen and hyaluronic acid to enhance the bioactivity of fibrin-based hydrogels for nucleus pulposus regeneration
(2018)Hydrogels, such as fibrin, offer a promising delivery vehicle to introduce cells into the intervertebral disc (IVD) to regenerate damaged disc tissue as a potential treatment for low back pain. However, fibrin lacks key ... -
Inferred Threat and Safety: Symbolic Generalization of Human Avoidance Learning
(2011)Symbolic generalization of avoidance may underlie the etiology and maintenance of anxiety disorders. The aim of the present study was to demonstrate inferred threat-avoidance and safety (non-avoidance) behaviours that occur ... -
The Influence of Additive Manufacturing Processes on the Performance of a Periodic Acoustic Metamaterial
(2019)Advancements in 3D print technology now allow the printing of structured acoustic absorbent materials at the appropriate microscopic scale and sample sizes. The repeatability of the fundamental cell unit of these metamaterials ...
