Browsing Mechanical & Manufacturing Eng (Theses and Dissertations) by Title
Now showing items 64-83 of 217
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Control of a Dynamic Wheeled-legged Robot Powered by Electric-Pneumatic Actuators
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)The implementation of wheels on the end distal of a mobile robot's leg is a design approach that is gaining increasing popularity as it enables improved energy efficiency, stability and adaptive locomotion strategies in ... -
Cooling by high speed air jet in orthogonal machining operations
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2012)Changing environmental awareness has led manufacturing industry to give critical consideration to the use of conventional coolants and traditional cooling techniques in machining processes. Current research shows that ... -
Deciphering the Molecular Mechanisms of Stem Cell Mechanotransduction: A New Avenue for the Development of Therapeutics for Osteoporosis
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)Osteoporosis is characterised by reduced bone density and weakened bone architecture leading to high fracture risk. The changes in bone result from an imbalance in the bone remodelling cycle whereby the rate of resorption ... -
Density Optimisation & In-Situ Microstructure Decomposition of As-Built Selective Laser Melted Ti-6Al-4V
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Additive manufacturing of titanium provides many advantages over traditional methodologies such as the ability to produce complex parts at no additional cost. One such AM method, selective laser melting (SLM) is a powder ... -
Design and development of a pre-clinical test for cemented femoral hip replacements
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)Current state of the art testing methods do not allow implant performance to be assessed relative to known failure modes, prior to clinical use. Even clinically, it can take up to 5 years before implant performance can be ... -
Design and optimisation of focused infrared heating devices
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020) -
Design, manufacture, modelling and testing of surface acoustic wave strain sensors
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2008)There is an increasing demand for multi-sensor strain measurement systems, particularly those which incorporate wireless sensors. A possible application of such a system is the Real-Time Weigh-In-Motion (RTWIM) of heavy ... -
Developing Microphysiological Systems of Bone Development, Physiology, and Repair
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Accurate models of human tissues and organ systems are foundational in our efforts to better understand human physiology. In the context of bone, a number of in vitro and in vivo models have been developed that facilitate ... -
Development and characterization of corneal substitutes from decellularized tissues
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)Diseases affecting the cornea can lead to vision impairment and ultimately to blindness. It is estimated that 45 million people worldwide suffer from corneal blindness. Rejection in high-risk patients and donor shortage ... -
Development and Functional Assessment of a Decellularised Injectable Biomaterial Combined with Nasal Chondrocytes for Intervertebral Disc Regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Lower Back Pain (LBP) is known to be a major health issue worldwide with a significant socioeconomic impact and it is widely accepted that LBP is associated with degeneration of the intervertebral disc (IVD). IVD degeneration ... -
The Development of a Novel 3D Bioprinting Strategy to Drive Vascularisation, and its Application for Bone Tissue Engineering
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)One of the major challenges facing the field of tissue engineering today is vascularisation. Without a system in place to circulate oxygen, nutrients and metabolites, the size of many tissue engineered constructs is ... -
Development of a performance framework to support the innovation process
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Performance frameworks (PFs) for measuring the innovation process are critical for both research and practice. However, existing PFs neglect performance indicators (PIs) and dimensions relevant to companies' current ... -
Development of an off-the-shelf biomimetic vascular graft for small diameter vascular regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)Cardiovascular disease is one of the leading causes of death worldwide. The impairment of blood flow can require a total vessel substitution, but current grafts fail to recapitulate the unique mechanical behavior of native ... -
The development of biomimetic scaffolds for osteochondral tissue engineering
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)Articular cartilage (AC) is a soft tissue lining the ends of the bones in our joints. Even minor lesions in AC cause pain, impaired mobility and can develop to osteoarthritis (OA), a disease affecting millions of adults ... -
Development of localised process parameter control for repeatability in metal additive manufacturing
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Due to the many advantages associated with metal additive manufacturing (AM) processes, research into these technologies has grown significantly over recent years. However, repeatability and reproducibility are critical ... -
Development of mechanobiomimetic strategies to drive stem cell behaviour for bone regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)There are a host of cases where clinical intervention must be taken to treat diseased or damaged bone, including severe fractures, defects, tumours requiring tissue removal, and debilitating diseases such as osteoporosis. ... -
Development, modelling and characterization of metal micro-textured thermal interface materials
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2010)A metal micro-textured thermal interface material (MMT-TIM) has been developed to address the shortcomings of conventional TIMs. In the present study, the MMT-TEVIs consist of silver foils with raised, small-scale, hollow ... -
Directional Solidification Experiments with the Transparent Model Alloy Neopentyl Glycol-35wt.%(D)Camphor
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)This thesis describes the development of an experimental facility in combination with image processing and computer vision techniques for the visualisation and characterisation of dendritic growth structures in the transparent ... -
EHD augmentation of convective boiling within a transparent heat exchange
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2013)This work investigated the influence of electrohydrodynamic forces on the two-phase flow patterns of HFE7000 refrigerant under convective boiling conditions. A flow loop was constructed which featured two novel transparent ... -
Electroconductive Biomaterial Platforms: from Piezoresistive Sensors to Cardiac Tissue Engineering
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)New classes of functional materials and the rapid advances being made in manufacturing technologies are key requirements to drive the next step forward in healthcare. In recent decades, conjugated polymers have gained ...