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Now showing items 47-66 of 149

  • Deciphering the Molecular Mechanisms of Stem Cell Mechanotransduction: A New Avenue for the Development of Therapeutics for Osteoporosis 

    CORRIGAN, MICHELE (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)
    Osteoporosis is characterised by reduced bone density and weakened bone architecture leading to high fracture risk. The changes in bone result from an imbalance in the bone remodelling cycle whereby the rate of resorption ...
  • Design and development of a pre-clinical test for cemented femoral hip replacements 

    Maher, Suzanne Adele (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)
    Current state of the art testing methods do not allow implant performance to be assessed relative to known failure modes, prior to clinical use. Even clinically, it can take up to 5 years before implant performance can be ...
  • Design, manufacture, modelling and testing of surface acoustic wave strain sensors 

    Mc Cormack, Brian (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2008)
    There is an increasing demand for multi-sensor strain measurement systems, particularly those which incorporate wireless sensors. A possible application of such a system is the Real-Time Weigh-In-Motion (RTWIM) of heavy ...
  • Development of mechanobiomimetic strategies to drive stem cell behaviour for bone regeneration 

    EICHHOLZ, KIAN (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)
    There are a host of cases where clinical intervention must be taken to treat diseased or damaged bone, including severe fractures, defects, tumours requiring tissue removal, and debilitating diseases such as osteoporosis. ...
  • Development, modelling and characterization of metal micro-textured thermal interface materials 

    Kempers, Roger (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2010)
    A metal micro-textured thermal interface material (MMT-TIM) has been developed to address the shortcomings of conventional TIMs. In the present study, the MMT-TEVIs consist of silver foils with raised, small-scale, hollow ...
  • EHD augmentation of convective boiling within a transparent heat exchange 

    McGranaghan, Gerard Joseph (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2013)
    This work investigated the influence of electrohydrodynamic forces on the two-phase flow patterns of HFE7000 refrigerant under convective boiling conditions. A flow loop was constructed which featured two novel transparent ...
  • Engineering tissues with a zonal structure and composition mimicking native articular cartilage 

    Luo, Lu (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2015)
    Engineering cartilage grafts with comparable functionality to the native tissue remains a major challenge in the field of regenerative medicine. The overall goal of this thesis was to engineer a cartilage graft with ...
  • Experimental investigations in turbomachinery noise-source identification 

    Davis, Ian (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2014)
    The exact contribution of each of the various core-noise sources within modern turboshaft engines to the noise radiated from the engine exhaust and into the surrounding environment is poorly understood. The objective of ...
  • Failure mechanisms in bone - a mechanical and histological study 

    Mercy, Matthew Vincent (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2006)
    Repeated loading causes the development of microdamage in bone and may lead to failure by fatigue. Microdam age in the form of microcracks occurs naturally in bone due to the loads experienced during day-to-day activities, ...
  • Failure of cemented hip implants under complex loading : experimental and numerical analysis 

    Britton, John Robert (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2004)
    A new generation of experimental pre-clinical testing methods for cemented hip replacement femoral components have been proposed, and preliminarily validated by comparing a 'good' prosthesis design with a 'bad' prosthesis ...
  • Finite element analysis & Die profile optimisation for a cold forging process 

    MacCormack, Conor (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2001)
    Throughout the world, almost every machine that moves requires the use of bolts in one form or another. Bolts, or Fasteners, are made in bolt making machines by a process of cold forming. At a particular stage in the bolt ...
  • Finite element and experimental analysis of dented aircraft panels 

    Lacey, Kevin (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2005)
    Aircraft fuselage panels are susceptible to low velocity impact damage in the form of "dents" from a variety of in-service sources, such as cargo and service trucks, dropped tools during servicing, walking on "no-step ...
  • Finite element and experimental analysis of the micro-form rolling process 

    Cregan, Emmet (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2007)
    The observations made during this research which, to the best knowledge of the author have not been previously mentioned in literature, were as follows: -- Loss of contact between the die and workpiece when rolling small ...
  • Finite element simulation of a metal forming process & die design 

    Quinlan, Gavin Edward (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)
    Thread Rolling (also known as roll threading) is a cold forming process for producing threads or other helical or annular forms on a fastener. This is achieved by rolling the surface profile of hardened steel dies onto the ...
  • Flow structures and heat transfer enhancement in the wakes of sliding bubbles 

    O'Reilly Meehan, Rudi (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2016)
    The motion of a bubble through a fluid has attracted considerable scientific attention for many years due to the complex, interesting fluid dynamics in their wakes, coupled to a rich and varied interface motion. Additionally, ...
  • FPGA based solver for internet eigenvectors 

    McGettrick, Séamas (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2010)
    Calculating an Internet Eigenvector for Internet ranking is a massive computational problem dominated by Sparse Matrix by Vector Multiplication (SMVM) where the matrix is very sparse, unsymmetrical and unstructured. The ...
  • Fracture and fatigue in High Impact Polystyrene : the influence of secondary phase morphology (Rubber Particle Size and Effective Rubber Phase Volume) on fracture and fatigue behaviour in HIPS 

    Dolan, Finbar (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2004)
    The subject of the following thesis is the influence of the secondary phase morphology on fracture and fatigue behaviour in High Impact Polystyrene (HIPS). The motivation of the work was the premature failure of parts ...
  • Fundamental Insights into Arterial Remodelling; Strain-Mediated Degradation of Arterial Collagen 

    GAUL, ROBERT (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)
    Maladaptive remodelling of structurally significant collagen fibres in the arterial wall is believed to play a critical role in the development and progression of degenerative arterial disease. A greater understanding of ...
  • Heat transfer characteristics of swirling impinging jets 

    Brown, Karl J. (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2013)
    The application of impinging jets for cooling purposes is an ongoing search for greater levels of heat dissipation in a world where manufacturing processes are getting more advanced and electrical systems are becoming ...
  • Hydrodynamics and heat transfer of laminar pulsating flow in a rectangular channel 

    Blythman, Richard (Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2017)
    The exploitation of flow pulsation is a potentially useful technique for enhanced cooling in single-phase cooling systems. This thesis contains parametric analyses of the hydrodynamics and heat transfer of a laminar ...