Browsing Clinical Medicine (Scholarly Publications) by Subject "macrophage"
Now showing items 1-3 of 3
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Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis.
(2014)Aging results in deterioration of the immune system, which is associated with increased susceptibility to infection and impaired wound healing in the elderly. Phagocytosis is an essential process in both wound healing and ... -
Attenuated CSF-1R signalling drives cerebrovascular pathology
(2021)Cerebrovascular pathologies occur in up to 80% of cases of Alzheimer's disease; however, the underlying mechanisms that lead to perivascular pathology and accompanying blood–brain barrier (BBB) disruption are still not ... -
Btk regulates macrophage polarization in response to lipopolysaccharide.
(2014)Bacterial Lipopolysaccharide (LPS) is a strong inducer of inflammation and does so by inducing polarization of macrophages to the classic inflammatory M1 population. Given the role of Btk as a critical signal transducer ...