Browsing Clinical Medicine (Scholarly Publications) by Subject "leukemia"
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Bcr-Abl regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation is required for proliferation and drug resistance (2006)The BCR-ABL oncogene is the hallmark of chronic myeloid leukemia, a clonal hematopoietic stem cell disorder. BCR-ABL displays constitutive tyrosine kinase activity, required for its transformation ability. Although the ...