Browsing Microbiology (Scholarly Publications) by Sponsor "Health Research Board"
Now showing items 1-3 of 3
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Anti-malarial effects of macrolactones related to FK520 (ascomycin) are independent of the immunosuppressive properties of the compounds
(University of Chicago Press, 2005)The polyketide macrolactone FK506 inhibits the growth of Plasmodium falciparum in culture and the enzymatic (peptidyl-prolyl cis-trans isomerase [PPIase]) and chaperone activities of a recently identified P. falciparum ... -
Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.
(Elsevier, 2009)We have selected piperaquine (PQ) and lumefantrine (LM) resistant Plasmodium berghei ANKA parasite lines in mice by drug pressure. Effective doses that reduce parasitaemia by 90% (ED90) of PQ and LM against the parent line ... -
A potential new pathway for Staphylococcus aureus dissemination: silent survival of S.aureus phagocytosed by human monocyte-derived macrophages.
(2008)Although considered to be an extracellular pathogen, Staphylococcus aureus is able to invade a variety of mammalian, non-professional phagocytes and can also survive engulfment by professional phagocytes such as neutrophils ...