Browsing Microbiology (Scholarly Publications) by Author "FOSTER, TIMOTHY"
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Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus
GEOGHEGAN, JOAN; FOSTER, TIMOTHY (2014)Staphylococcus aureus is an important opportunistic pathogen and persistently colonizes about 20% of the human population. Its surface is 'decorated' with proteins that are covalently anchored to the cell wall peptidoglycan. ... -
Analysis of tetracycline resistance encoded by transposon Tn10: deletion mapping of tetracycline-sensitive point mutations and identification of two structural genes
FOSTER, TIMOTHY (1983)Deletions in the tet genes derived from Tn10 were formed from different tet::Tn5 insertion mutations by removing DNA sequences located between a HindIII site in Tn5 and a HindIII site adjacent to the tet genes. ... -
The binding of calcium to the B-repeat segment of SdrD, a cell surface protein of Staphylococcus aureus
FOSTER, TIMOTHY (1998)In the Sdr family of Staphylococcus aureus cell surface proteins, three recently cloned members (Josefsson, E., McCrea, K., Ni Eidhin, D., O'Connell, D., Cox, J. A., Hook, M., and Foster, T. (1998) Microbiology, in press) ... -
Clumping factor A interaction with complement factor I increases C3b cleavage on the bacterial surface of Staphylococcus aureus, and decreases complement-mediated phagocytosis
FOSTER, TIMOTHY; GEOGHEGAN, JOAN (2010)The human complement system is important in the immunological control of Staphylococcus aureus infection. We showed previously that S. aureus surface protein clumping factor A (ClfA), when expressed in recombinant form, ... -
Clumping factor A of Staphylococcus aureus inhibits phagocytosis by human polymorphonuclear leucocytes
FOSTER, TIMOTHY (2006)Staphylococcus aureus is a major cause of nosocomial and community-acquired infection. It expresses several factors that promote avoidance of phagocytosis by polymorphonuclear leucocytes. Clumping factor A (ClfA) is a ... -
Clumping factor B promotes adherence of Staphylococcus aureus to corneocytes in atopic dermatitis
IRVINE, ALAN; GEOGHEGAN, JOAN; FOSTER, TIMOTHY; FALLON, PADRAIC (2017) -
Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation
FOSTER, TIMOTHY (2016)Staphylococcus lugdunensis is a coagulase negative bacterial pathogen that is particularly associated with severe cases of infectious endocarditis. Unique amongst the coagulase-negative staphylococci, S. lugdunensis harbors ... -
Complement regulator C4BP binds to Staphylococcus aureus surface proteins SdrE and Bbp inhibiting bacterial opsonization and killing.
GEOGHEGAN, JOAN; FOSTER, TIMOTHY (2013)Staphylococcus aureus is a premier human pathogen and the most common cause of osteoarticular, wound, and implanted device infections. We recently demonstrated S. aureus efficiently binds the classical complement regulator ... -
Complete bypass of restriction systems for major staphylococcus aureus lineages
FOSTER, TIMOTHY (2015)Staphylococcus aureus is a prominent global nosocomial and community-acquired bacterial pathogen. A strong restriction barrier presents a major hurdle for the introduction of recombinant DNA into clinical isolates of S. ... -
Deletion map of the chloramphenicol resistance region of R1 and R100-1
FOSTER, TIMOTHY (1973)Recombination between single-site and multisite chloramphenicol-sensitive mutants of the F-like R factors R1 and R100-1 indicates that the chloramphenicol resistance region is a single structural gene coding for the ... -
Deletions in the r-determinant mer region of plasmid R100-1 selected by loss of mercury hypersensitivity
FOSTER, TIMOTHY (1979)A mutant of plasmid R100-1, which conferred cellular hypersensitivity to Hg2+ because of the insertion of Tn801 (TnA) into the gene determining synthesis of mercuric reductase enzyme, allowed further mutational events to ... -
Design and characterisation of food grade powders and inks for microstructure control using 3D printing
FOSTER, TIMOTHY (2018)Additive Manufacturing techniques have been previously applied to food materials with direct consumption in mind, as opposed to creating structural ingredients as shown in this study. First, semi-crystalline cellulose was ... -
The dipeptide repeat region of the fibrinogen-binding protein (clumping factor) is required for functional expression of the fibrinogen-binding domain on the Staphylococcus aureus cell surface.
FOSTER, TIMOTHY (1997)Clumping factor of Staphylococcus aureus is a fibrinogen‐binding protein that is located on the bacterial cell surface. The protein has an unusual repeat domain (region R) comprising mainly the dipeptide aspartate and ... -
Direct interaction of iron-regulated surface determinant IsdB of Staphylococcus aureus with the GPIIb/IIIa receptor on platelets
FOSTER, TIMOTHY; GEOGHEGAN, JOAN (2010) -
Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus
FALLON, PADRAIC; IRVINE, ALAN; FOSTER, TIMOTHY (2011)