Browsing Psychology (Scholarly Publications) by Author "O'MARA, SHANE"
Now showing items 1-20 of 20
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The anterior thalamus provides a subcortical circuit supporting memory and spatial navigation.
(2013)The anterior thalamic nuclei (ATN), a central component of Papez' circuit, are generally assumed to be key constituents of the neural circuits responsible for certain categories of learning and memory. Supporting evidence ... -
Automated spike sorting algorithm based on Laplacian eigenmaps and k-means clustering
(2011)This study presents a new automatic spike sorting method based on feature extraction by Laplacian eigenmaps combined with k-means clustering. The performance of the proposed method was compared against previously reported ... -
Chronic immobilization stress occludes in vivo cortical activation in an animal model of panic induced by carbon dioxide inhalation.
(2014)Breathing high concentrations of carbon dioxide (CO2) can trigger panic and anxiety in humans. CO2 inhalation has been hypothesized to activate neural systems similar to those underlying fear learning, especially those ... -
Decoding signal processing in thalamo-hippocampal circuitry: Implications for theories of memory and spatial processing
(2015)A major tool in understanding how information is processed in the brain is the analysis of neuronal output at each hierarchical level through which neurophysiological signals are propagated. Since the experimental brain ... -
Dissociation of dorsal hippocampal regional activation under the influence of stress in freely behaving rats.
(2011)Stress has deleterious effects on brain, body, and behavior in humans and animals alike. The present work investigated how 30-min acute photic stress exposure impacts on spatial information processing in the main sub-regions ... -
Hippocampal-anterior thalamic pathways for memory: uncovering a network of direct and indirect actions.
(2010)This review charts recent advances from a variety of disciplines that create a new perspective on why the multiple hippocampal?anterior thalamic interconnections are together vital for human episodic memory and rodent event ... -
Impaired capacity for autonoetic reliving during autobiographical event recall in mild Alzheimer's disease
(2011)The capacity to mentally travel back in time and relive past events via autonoetic consciousness has been shown to be compromised even in the early stages of Alzheimer's disease (AD). To further understand the unravelling ... -
The irregular firing properties of thalamic head direction cells mediate turn-specific modulation of the directional tuning curve.
(2014)HEAD DIRECTION (HD) cells in anterior thalamus express a wide range of interspike intervals (ISIs) (Taube 2010). Given the importance of HD encoding for spatial navigation in the environment, it is crucial to understand ... -
Nucleus reuniens of the thalamus contains head direction cells.
(2014)Discrete populations of brain cells signal heading direction, rather like a compass. These 'head direction' cells are largely confined to a closely-connected network of sites. We describe, for the first time, a population ... -
Objects & Place cells in Claustrum
(Trinity College Dublin, 2015) -
Prolonged rote learning produces delayed memory facilitation and metabolic changes in the hippocampus of the ageing human brain
(2009)Background: Repeated rehearsal is one method by which verbal material may be transferred from short- to long-term memory. We hypothesised that extended engagement of memory structures through prolonged rehearsal would ... -
The psychostimulant modafinil facilitates water maze performance and augments synaptic potentiation in dentate gyrus
(2010)Modafinil is a psychostimulant drug used widely for the treatment of narcolepsy, which also has additional positive effects on cognition. Here, we investigate the effects of modafinil on behavioral performance and synaptic ... -
Quantitative MRI analysis of brain volume changes due to controlled cortical impact.
(2010)More than 85% of reported brain traumas are classified clinically as "mild" using the Glasgow Coma Scale (GCS); qualitative MRI findings are scarce and provide little correspondence to clinical symptoms. Our goal, therefore, ... -
Respiratory cycle entrainment of septal neurons mediates the fast coupling of sniffing rate and hippocampal theta rhythm.
(2014)Memory for odour information may result from temporal coupling between the olfactory and hippocampal systems. Respiration defines the frequency of olfactory perception, but how the respiratory rate affects hippocampal ... -
Respiratory cycle entrainment of septal neurons mediates the fast coupling of sniffing rate and hippocampal theta rhythm.
(2014)Memory for odour information may result from temporal coupling between the olfactory and hippocampal systems. Respiration defines the frequency of olfactory perception, but how the respiratory rate affects hippocampal ... -
Risk factors for the development of depression in patients with Hepatitis C taking Interferon-alpha.
(2010)Interferon-?, currently used for the treatment of hepatitis C, is associated with a substantially elevated risk of depression. However, not everyone who takes this drug becomes depressed, so it is important to understand ... -
Segregation of parallel inputs to the anteromedial and anteroventral thalamic nuclei of the rat
(2013)Many brain structures project to both the anteroven tral thalamic nucleus and the anteromedial thalamic nucleus. In the present stud y, pairs of different tracers were placed into these two thalamic sites in the same ... -
Suppressing the encoding of new information: A behavioral study derived from principles of hippocampal function.
(2013)Cognitive processes do not occur in isolation. Interactions between cognitive processes can be observed as a cost in performance following a switch between tasks, a cost that is greatest when the cognitive requirements ...
