Browsing Biochemistry (Scholarly Publications) by Sponsor "European Research Council (ERC)"
Now showing items 1-3 of 3
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Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
(Springer Nature, 2023-03-08)Metabolic rewiring underlies the effector functions of macrophages, but the mechanisms involved remain incompletely defined. Here, using unbiased metabolomics and stable isotope-assisted tracing, we show that an inflammatory ... -
Natural Killer cells integrate signals received from tumour interactions and IL2 to induce robust and prolonged anti-tumour and metabolic responses
(2019)Natural Killer (NK) cells are lymphocytes with an important role in anti-tumour responses. NK cells bridge the innate and adaptive arms of the immune system; they are primed for immediate anti-tumour function but can also ... -
The role of Ets2 transcription factor in the induction of microRNA-155 by LPS, and its targeting by IL-10.
(2014)MicroRNA-155 (miR-155) is highly expressed in many cancers such as B cell lymphomas and myeloid leukaemia, and inflammatory disorders such as rheumatoid arthritis, atopic dermatitis and multiple sclerosis. The role ...
