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  • Sestrins Link Tumor Suppressors with the AMPK -TOR Signaling Network 

    Budanov, Andrei (InTech, 2012)
    The strength of the mechanisms involved in the control of health and lifespan determines the rate of aging in any organism. Aging is fueled by the accumulation of damage in a multitude of tissues, causing many age-related ...
  • Stressin' Sestrins take an aging fight 

    Budanov, Andrei; Lee, Jun Hee; Karin, Michael (2010)
    Sestrins (Sesns) are a family of highly conserved stress‐responsive proteins, transcriptionally regulated by p53 and forkhead transcription factor that exhibit oxidoreductase activity in vitro and can protect cells from ...