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  • An examination of the molecular control of feed efficiency in beef cattle 

    MCKENNA, CLARE (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)
    Global agriculture is faced with the enormous challenge of feeding a rapidly growing population while being cognizant of the environmental footprint of such endeavours. A consequence of increased meat consumption worldwide ...
  • Functional Relevance of Interleukin 8 Haplotype for the Innate Immune System in Holstein-Friesian Cattle 

    O'Brien, Megan (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2021)
    Calves rely heavily on their innate immune response in the post-birth period before their adaptive immune system develops. Interleukin 8 (IL-8) is a major chemoattractant predominantly associated with neutrophils response ...
  • Genetic variation in bulls divergent for fertility 

    WHISTON, RONAN (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2017)
    Bovine fertility remains a critical issue underpinning the sustainability of the agricultural sector. Since the realisation of an unfavourable relationship between fertility and production traits in cattle, methods to ...
  • Innate immune phenotype variation in bovine health and disease 

    Reid, Cian Michael (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)
    Infectious diseases are estimated to cost the global agriculture industry $300 billion annually and present significant challenges to animal welfare. Disease burden in cattle and other livestock species also threaten ...
  • Innate immune potential of bovine respiratory epithelial cells: role in viral infection 

    Swoboda, Sarah (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)
    Respiratory epithelial cells have important defence activities against respiratory viruses. While their physical barrier function is well described, the molecular mechanisms responsible for how epithelial cells initiate, ...
  • Regulation of bovine beta-defensin expression 

    Barry-Reidy, Anne (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2017)
    Beta-defensins are a class of host defence peptides with antibacterial, antiviral and immunomodulatory roles. The bovine genome contains up to 57 putative beta-defensin genes in four syntenic clusters on different chromosomes. ...