Browsing Medical Gerontology (Scholarly Publications) by Subject "Genes & Society"
Now showing items 1-7 of 7
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Control of HIV infection by IFN-α: implications for latency and a cure.
(Springer, 2018)Viral infections, including HIV, trigger the production of type I interferons (IFNs), which in turn, activate a signalling cascade that ultimately culminates with the expression of anti-viral proteins. Mounting evidence ... -
Integrating genotypic data with transcriptomic and proteomic data.
(2002)Historically genotypic variation has been detected at the phenotypic level, at the metabolic level, and at the protein chemistry level. Advances in technology have allowed its direct visualisation at the level of DNA ... -
Lack of association between angiotensin-converting enzyme genotype and muscle strength in Peruvian older people
(2020)Aging can be associated with decreasing muscle strength, and related factors are comorbidities, sex, physical activity, and possibly genetic factors. Among genetic factors the renin-angiotensin system is of interest, but ... -
Orthostatic hypotension and novel blood pressure associated gene variants in older adults: data from the TILDA Study
(2020)Orthostatic hypotension (OH) is associated with increased risk of trauma and cardiovascular events. Recent studies have identified new genetic variants that influence orthostatic blood pressure (BP). The aim of this study ... -
SNP variation in the promoter of the PRKAG3 gene and association with meat quality traits in pig.
(2012)Background The PRKAG3 gene encodes the ?3 subunit of adenosine monophosphate activated protein kinase (AMPK), a protein that plays a key role in energy metabolism in skeletal muscle. Non-synonymous single nucleotide ... -
Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation
(2017)Low socioeconomic status (SES) is associated with earlier onset of age-related chronic conditions and reduced life-expectancy, but the underlying biomolecular mechanisms remain unclear. Evidence of DNA-methylation differences ...