Browsing Medical Gerontology (Scholarly Publications) by Subject "Frailty"
Now showing items 21-40 of 41
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Home FIRsT: interdisciplinary geriatric assessment and disposition outcomes in the Emergency Department
(2020)Background: Older people in the Emergency Department (ED) are clinically heterogenous and some presentations may be better suited to alternative out-of-hospital pathways. A new interdisciplinary comprehensive geriatric ... -
Impairments in Hemodynamic Responses to Orthostasis Associated with Frailty: Results from The Irish Longitudinal Study on Ageing (TILDA)
(2018)Objectives: To characterize the relationships between orthostatic blood pressure (BP) and heart rate recovery and frailty in an older population. Design: Cross-sectional study. Setting: Two health centers in the Republic ... -
The Importance of Age in the Prediction of Mortality by a Frailty Index: A Machine Learning Approach in the Irish Longitudinal Study on Ageing
(2021)The quantification of biological age in humans is an important scientific endeavor in the face of ageing populations. The frailty index (FI) methodology is based on the accumulation of health deficits and captures variations ... -
Interrupting Bedtime to Reverse Frailty Levels in Acute Care: A Study Protocol for the Breaking Bad Rest Randomized Controlled Trial
(2023)Background Hospitalized older patients spend most of the waking hours in bed, even if they can walk independently. Excessive bedrest contributes to the development of frailty and worse hospital outcomes. We describe the ... -
Involving older people in co-designing a primary-care intervention to reverse frailty and build resilience
(2021)Background: An essential consideration in health research is to conduct research with members of the public rather than for them. Public and patient involvement (PPI) of older people in research can improve enrolment, ... -
Is phenotypical prefrailty all the same? A longitudinal investigation of two prefrailty subtypes in TILDA
(2019)Background: Fried's frailty phenotype is defined by five criteria: exhaustion, unexplained weight loss, weakness, slowness and low physical activity. Prefrailty (PF) meets one or two criteria. PF is of interest as a target ... -
Lack of association between angiotensin-converting enzyme genotype and muscle strength in Peruvian older people
(2020)Aging can be associated with decreasing muscle strength, and related factors are comorbidities, sex, physical activity, and possibly genetic factors. Among genetic factors the renin-angiotensin system is of interest, but ... -
A linear regression-based machine learning pipeline for the discovery of clinically relevant correlates of gait speed reserve from multiple physiological systems
(2021)Frailty in older adults is characterized by reduced physiological reserve. Gait speed reserve (GSR: maximum minus usual gait speed) could help identify frailty and act as a proxy for physiological reserve. Utilizing data ... -
The Lived Experience of Frailty: Beyond Classification and Towards a Holistic Understanding of Health
(2024)Purpose: Frailty is characterised by decreased physiological reserves and vulnerability to stressors. Although scales such as the Fried’s Frailty Phenotype (FP), Frailty Index (FI), and Clinical Frailty Scale (CFS) are ... -
Measuring Frailty using Self-report and Test-based Health Measures.
(2015)Background: previously, frailty indices were constructed using mostly subjective health measures. The reporting error in this type of measure can have implications on the robustness of frailty findings. Objective: to ... -
Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults
(2021)In this Specialty Grand Challenge, we outline our vision of the current challenges in the field of Network Physiology as applied to aging and frailty. An expected development in this field for the 21st century is the ... -
Primary care interventions to address physical frailty among community-dwelling adults aged 60 years or older: A meta-analysis
(2020)Introduction: The best interventions to address frailty among older adults have not yet been fully defined, and the diversity of interventions and outcome measures makes this process challenging. Consequently, there is ... -
Protocol for a randomised controlled trial of a primary care intervention to Reverse Frailty and Enhance Resilience through Exercise and dietary protein Education (REFEREE) in community-dwelling adults aged 65 and over
(2020)Introduction: Resistance exercises and dietary protein have been shown to reverse frailty, yet they are not commonly offered in clinical practice. We aim to measure changes in health outcomes, including physical frailty ... -
The relationship between increased body mass index and frailty on falls in community dwelling older adults
(2013)Background The global population is becoming older and more overweight. The inter-relationship between frailty and falls is often seen in the older adult and is associated with poor health outcomes. Little is known about ... -
The Syncope-Falls Index (SYFI): A tool for predicting risk of syncope and complex falls in the older adult based on cumulative health deficits
(2021)Background Syncope is aetiologically diverse and associated with adverse outcomes; in older people, there is clinical overlap with complex falls presentations (i.e. recurrent, unexplained, and/or injurious). Aim To ... -
Testing the feasibility of a primary-care exercise intervention to prevent and reverse early frailty and build resilience in community-dwelling older adults
(2022)Background: Resistance exercises have been shown to prevent and reverse frailty but their application in clinical practice is low. We wished to test the feasibility of an optimised exercise intervention for mild or pre-frailty ... -
Transitions between degrees of multidimensional frailty among older people admitted to intermediate care: a multicentre prospective study
(2022)Background: Frailty is a dynamic condition that is clinically expected to change in older individuals during and around admission to an intermediate care (IC) facility. We aimed to characterize transitions between degrees ... -
Transitions in frailty phenotype states and components over 8 years: evidence from The Irish Longitudinal Study on Ageing
(2021)Aim: Fried's frailty phenotype (FP) is defined by exhaustion (EX), unexplained weight loss (WL), weakness (WK), slowness (SL) and low physical activity (LA). Three or more components define the frail state, and one or two ... -
Turkish version of the SHARE-Frailty Instrument for primary care: reliability and validity in the nursing home setting
(2023)In Turkey, physical frailty instruments have not been studied in the nursing home setting. We determined the reliability and validity of a Turkish version of the SHARE-Frailty Instrument for primary care (SHARE-FI) in ...