Browsing Psychiatry (Scholarly Publications) by Title
Now showing items 229-248 of 361
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Lack of gender effect on familial schizophrenia. A Brazilian study.
(Arquivos de Neuro Psiquiatria / Academia Brasileira de Neurologia - ABNEURO, 2000)Estudos epidemiologicos em esquizofrenia estabeleceram que a idade de inicio para o genero masculino precede em alguns anos aquela para o feminino. No entanto, tal efeito de genero n?o vem sendo observado para os casos ... -
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
(2020)We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n = 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to integrate de novo and case-control rare variation, ... -
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
(2019)Cranial growth and development is a complex process which affects the closely related traits of head circumference (HC) and intracranial volume (ICV). The underlying genetic influences shaping these traits during the ... -
Mental health problems in children with prader-willi syndrome.
(2012)BACKGROUND: Prader-Willi Syndrome (PWS) is a genetically determined neurodevelopmental disorder, which occurs in approximately one in 22000 births. AIMS: This study aimed to investigate psychiatric characteristics of ... -
Mental Illness in Irish Prisoners
(National Forensic Mental Health Service, Dundrum, Dublin 14, Ireland, 2004-12)This is the first systematic and representative survey of psychiatric morbidity in the Irish Prison population, using standardised research diagnostic methods. Five samples have been compiled, including 7% of all men ... -
Mental state decoding v. mental state reasoning as a mediator between cognitive and social function in psychosis
(The Royal College of Psychiatrists, 2008)Theory of mind deficits in schizophrenia have been parsed into mental state reasoning and mental state decoding components. We report that mental state decoding as measured by the `Eyes task? better predicted social function ... -
Mental state decoding versus mental state reasoning as a mediator between cognitive and social function in psychosis
(2008)Theory of mind deficits in schizophrenia have been parsed into mental state reasoning and mental state decoding components. We report that mental state decoding as measured by the `Eyes task? better predicted social ... -
Methyl-CpG2-binding protein 2 mediates overlapping mechanisms across brain disorders
(2020)MECP2 and its product, Methyl-CpG binding protein 2 (MeCP2), are mostly known for their association to Rett Syndrome (RTT), a rare neurodevelopmental disorder. Additional evidence suggests that MECP2 may underlie other ... -
Microduplications of 16p11.2 are associated with schizophrenia
(Nature, 2009)Recurrent microdeletions and microduplications of a 600-kb genomic region of chromosome 16p11.2 have been implicated in childhood-onset developmental disorders. We report the association of 16p11.2 microduplications with ... -
Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms?
(2010)Mental disorders are a major cause of long-term disability and are a direct cause of mortality, with approximately 800.000 individuals dying from suicide every year worldwide ? a high proportion of them related to major ... -
MIR137HG risk variant rs1625579 genotype is related to corpus callosum volume in schizophrenia
(2015)Genome-wide association studies implicate the MIR137HG risk variant rs1625579 (MIR137HGrv) within the host gene for microRNA-137 as a potential regulator of schizophrenia susceptibility. We examined the influence of ... -
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).
(2014)It has long been recognized that generalized deficits in cognitive ability represent a core component of schizophrenia (SCZ), evident before full illness onset and independent of medication. The possibility of genetic ... -
Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility.
(2011)Susceptibility to schizophrenia and bipolar disorder may involve a substantial, shared contribution from thousands of common genetic variants each of small effect. Identifying if risk variants map to specific molecular ... -
Molecular signatures of response to mecasermin in children with Rett Syndrome
(2022)Rett syndrome (RTT) is a devastating neurodevelopmental disorder without effective treatments. Attempts at developing targetted therapies have been relatively unsuccessful, at least in part, because the genotypical and ...