Browsing Physiology (Scholarly Publications) by Author "MURPHY, NIAMH"
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Dok2 mediates the CD200Fc attenuation of Aß-induced changes in glia.
LYNCH, MARINA; MURPHY, NIAMH; COSTELLO, DEREK; DOWNER, ERIC (2012)Background: The interaction between the membrane glycoprotein, CD200 and its cognate receptor CD200 receptor (CD200R), has been shown to play a role in maintaining microglia in a quiescent state. There is evidence of ... -
The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation.
LYNCH, MARINA ANNETTA; MURPHY, NIAMH; GOWRAN, AOIFE; CAMPBELL, VERONICA ANN (2012)Background: Several factors contribute to the deterioration in synaptic plasticity which accompanies age and one of these is neuroinflammation. This is characterized by increased microglial activation associated with ...