Browsing Physiology (Scholarly Publications) by Author "Costello, Derek A."
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Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice.
Lynch, Marina; Kerskens, Christian; McIntosh, Allison; Mela, Virginia; Harty, Conor; Minogue, Aedin M.; Costello, Derek A.; Kerskens, Christian; Lynch, Marina A. (2019)Among the changes that typify Alzheimer’s disease (AD) are neuroinflammation and microglial activation, amyloid deposition perhaps resulting from compromised microglial function and iron accumulation. Data from Genome Wide ...