Browsing Immunology (Scholarly Publications) by Author "Kelly, Lynne"

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  • Increased systemic inflammation in children with Down syndrome 

    Molloy, Eleanor; Roche, Edna; Leahy, Ronan; Doherty, Derek; Franklin, Orla; Balfe, Joanne; Kelly, Lynne (2020)
    Children with Down syndrome (DS) develop more infections, have an increased mortality from sepsis and an increased incidence of chronic inflammatory conditions. Cytokine dysregulation may underpin these clinical sequelae ...

  • Melatonin as an immunomodulator in children with Down syndrome 

    Kelly, Lynne; Roche, Edna; Doherty, Derek (2022)
    Background: Down syndrome (DS) is a disorder characterised by marked immune dysfunction, increased mortality from sepsis, chronic inflammation, increased oxidative stress, sleep disturbance and possibly abnormal endogenous ...