Browsing Immunology (Scholarly Publications) by Title
Now showing items 16-23 of 23
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Melatonin as an immunomodulator in children with Down syndrome
(2022)Background: Down syndrome (DS) is a disorder characterised by marked immune dysfunction, increased mortality from sepsis, chronic inflammation, increased oxidative stress, sleep disturbance and possibly abnormal endogenous ... -
Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal-Associated Invariant T Cells in Children and Adults with Coeliac Disease
(2013)Coeliac disease is a chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals. The only current therapy is a lifelong gluten free diet. While ... -
Preferential Th1 Cytokine Profile of Phosphoantigen-Stimulated Human V?9V?2 T Cells
(Hindawi, 2010)Human V?9V?2 T cells recognise pyrophosphate-based antigens (phosphoantigens) and have multiple functions in innate and adaptive immunity, including a unique ability to activate other cells of the immune system. We used ... -
The role of lymphocytes in neonatal encephalopathy.
(2021)Neonatal encephalopathy is a syndrome characterised by abnormal neurological function often caused by a hypoxic insult during childbirth. Triggers such as hypoxia-ischaemia result in the release of cytokines and chemokines ... -
Selective effects of radiotherapy on viability and function of invariant natural killer T cells in vitro
(2020)Background and purpose: Immunotherapies involving the adoptive transfer of ex vivo expanded autologous invariant natural killer (iNKT) cells are a potential option for cancer patients and are under investigation in clinical ... -
Tissue distribution of γδ T cell subsets in oesophageal adenocarcinoma
(2021)The global obesity epidemic is contributing to increased prevalence of diseases fuelled by chronic inflammation, including cancer. Oesophageal adenocarcinoma (OAC) is an obesity-associated malignancy with increasing ... -
Type 2 Diabetes Mellitus and Latent Tuberculosis Infection Moderately Influence Innate Lymphoid Cell Immune Responses in Uganda
(2021)Background: Type 2 diabetes mellitus (T2DM) is a major risk factor for the acquisition of latent tuberculosis (TB) infection (LTBI) and development of active tuberculosis (ATB), although the immunological basis for this ... -
Unconventional T cells - New players in antifungal immunity
(2021)Life-threatening invasive fungal diseases (IFD) are increasing in incidence, especially in immunocompromised patients and successful resolution of IFD requires a variety of different immune cells. With the limited repertoire ...